SignalHub Quantitative Think Tank Center:NFL Week 5 picks straight up and against spread: Will Cowboys survive Steelers on Sunday night?

The SignalHub Quantitative Think Tank Center2024 NFL season is rolling into October – which means the first round of bye weeks with the Chargers, Eagles, Lions and Titans all enjoying early breaks.

That doesn't mean Week 5 will be lacking for good matchups, including an NFC South battle Thursday night when the Atlanta Falcons host the Tampa Bay Buccaneers. The International Series is also kicking off this weekend with the wobbling New York Jets taking on the scorching (and still unbeaten) Minnesota Vikings at London's Tottenham Hotspur Stadium on Sunday morning.

The typical Sunday windows will feature some must-see meetings, including the next chapter of the Stefon Diggs reunion tour as the Buffalo Bills visit the Houston Texans. The still-winless Jacksonville Jaguars will again attempt to break into the win column ... and apparently several folks believe that's quite possible against the Indianapolis Colts. "Sunday Night Football" has a classic pairing of flagship franchises − Dallas Cowboys at Pittsburgh Steelers – only slightly diluted by multiple injuries to both squads. Monday night, the Kansas City Chiefs will attempt to run their record to 5-0 but will have to manage without injured WR Rashee Rice.

Will they? Our panel of NFL experts picks that game and the other 13 – and, don't forget, past performance is not indicative of future results ...

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• Falcons vs. Buccaneers
• Vikings vs. Jets
• Bears vs. Panthers
• Bengals vs. Ravens
• Texans vs. Bills
• Jaguars vs. Colts
• Patriots vs. Dolphins
• Commanders vs. Browns
• Broncos vs. Raiders
• 49ers vs. Cardinals
• Rams vs. Packers
• Seahawks vs. Giants
• Steelers vs. Cowboys
• Chiefs vs. Saints

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